![]() ![]() For example, the poison batrachotoxin – a highly poisonous steroidal alkaloid derived from various poison dart frogs, certain beetles, and birds – has no antidote, and as a result, is often fatal if it enters the human body in sufficient quantities. Some other toxins have no known antidote. Some animal venoms, especially those produced by arthropods (such as certain spiders, scorpions, and bees) are only potentially lethal when they provoke allergic reactions and induce anaphylactic shock as such, there is no "antidote" for these venoms however anaphylactic shock can be treated (e.g. This results in an antivenom that can be used to counteract venom produced by certain species of snakes, spiders, and other venomous animals. The antidotes for some particular toxins are manufactured by injecting the toxin into an animal in small doses and extracting the resulting antibodies from the host animals' blood. Antidotes for anticoagulants are sometimes referred to as reversal agents. The term ultimately derives from the Greek term φάρμακον ἀντίδοτον (pharmakon) antidoton, "(medicine) given as a remedy". His one great achievement is being the father of three amazing children.For other uses, see Antidote (disambiguation).Īn antidote is a substance that can counteract a form of poisoning. He is one of the founders of the FOAM movement (Free Open-Access Medical education) and is co-creator of , the RAGE podcast, the Resuscitology course, and the SMACC conference. He created the ‘Critically Ill Airway’ course and teaches on numerous courses around the world. He coordinates the Alfred ICU’s education and simulation programmes and runs the unit’s education website, INTENSIVE. He is actively involved in in using translational simulation to improve patient care and the design of processes and systems at Alfred Health. He has completed fellowship training in both intensive care medicine and emergency medicine, as well as post-graduate training in biochemistry, clinical toxicology, clinical epidemiology, and health professional education. He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives.Īfter finishing his medical degree at the University of Auckland, he continued post-graduate training in New Zealand as well as Australia’s Northern Territory, Perth and Melbourne. He is on the Board of Directors for the Intensive Care Foundation and is a First Part Examiner for the College of Intensive Care Medicine. He is also a Clinical Adjunct Associate Professor at Monash University. He is a co-founder of the Australia and New Zealand Clinician Educator Network (ANZCEN) and is the Lead for the ANZCEN Clinician Educator Incubator programme. consider intralipid if refractory to standard measuresĬhris is an Intensivist and ECMO specialist at the Alfred ICU in Melbourne.activated charcoal if 2-10mg/hr (traditional option but inferior to HIET).hyperkalaemia: Ca2+ gluconate, dextrose-insulin, NaHCO3, dialysis, salbutamol.METABOLIC: hypoglycaemia, hyperkalaemia.CVS: hypotension, bradycardia, AV block, heart failure.proportional to the type and amount ingested.sotalol -> causes potassium efflux blockade -> long QT -> monitor for Torsades propanolol -> causes sodium channel blockade -> QRS widening -> treat with NaHCO3 two beta-blockers require special consideration:.exceptions are those in the elderly those with decreased cardio-respiratory reserve, and those with co-ingestions of other cardiovascularly active agents.
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